Neuropsychiatric damage in Systemic Lupus Erythematosus: Possible protective role of medications.
نویسندگان
چکیده
منابع مشابه
Neuropsychiatric Systemic Lupus Erythematosus
Neuropsychiatric systemic lupus erythematosus (NPSLE) is the least understood, yet perhaps the most prevalent manifestation of lupus. The pathogenesis of NPSLE is multifactorial and involves various inflammatory cytokines, autoantibodies, and immune complexes resulting in vasculopathic, cytotoxic and autoantibody-mediated neuronal injury. The management of NPSLE is multimodal and has not been s...
متن کاملCatecholoestrogens: possible role in systemic lupus erythematosus.
It is well established that risk of developing SLE is higher among women compared with men but only very little is understood about the underlying mechanisms. Oestrogen and their catechol metabolites seem to play an important role in SLE but the exact patho-aetiology remains elusive. The evidences concerning the possibility of catecholoestrogens (CEs) in the development of SLE are very limited ...
متن کاملNeurobrucellosis in systemic lupus erythematosus
Background: Brucellosis is a zoonotic infection which is endemic in many countries. It is a multisystem disease which may present with a broad spectrum of clinical manifestations and complications. Neurobrucellosis is an uncommon complication of brucellosis. Case presentation: A 25-year-old woman with a history of lupus for 5 months referred to the emergency ward of Shahid Beheshti Hosp...
متن کاملNeuropsychiatric questionnaires in systemic lupus erythematosus.
Patients with systemic lupus erythematosus (SLE) can be affected by a multitude of neurologic and psychiatric symptoms with a wide range of prevalence and severity. Irrespectively from attribution to SLE or other causes, neuropsychiatric (NP) symptoms strongly impact short-term and long-term outcomes, thus NP evaluation during routine clinical practice in SLE should be undertaken regularly. The...
متن کاملMycophenolate mofetil in neuropsychiatric systemic lupus erythematosus.
Neuropsychiatric abnormalities frequently occur in patients with systemic lupus erythematosus, affecting as many as 14-75% of people with this disease. High-dose steroid with or without anticoagulation is the mainstay of treatment in neuropsychiatric systemic lupus erythematosus (NPSLE). Use of mycophenolate as a steroid sparing drug may be a potential alternative agent in the therapy of NPLE, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Revista de Neuro-Psiquiatria
سال: 2013
ISSN: 1609-7394,0034-8597
DOI: 10.20453/rnp.v71i1-4.1630